NMN, known as β-Nicotinamide Mononucleotide (NMN for short), is found in some fruits, vegetables and poultry meat and is a naturally occurring substance in the human body that is converted into NAD+, an important coenzyme associated with human metabolism. Studies have shown that intracellular NAD+ levels decrease with age, and exogenous supplementation of NMN is thought to have a beneficial effect in enhancing cellular function in the body. Studies have found that NAD+ levels steadily decay with age, leading to altered metabolism and increased disease susceptibility; restoring NAD+ levels in aged or diseased animals promotes health and prolongs lifespan.

　　Preclinical studies have shown multiple pharmacological effects of NMN in cardiac and cerebral ischaemia, Alzheimer's disease, diet and age-induced type 2 diabetes and obesity, all of which are associated with NAD+ deficiency.

　　Understanding and judging the efficacy of NMN should be based on the results of scientific studies and clinical trials; following the currently available literature, the research findings on the efficacy of NMN are summarised as follows.

　　1. support NAD+ production[1]

　　2. activation of SIRTUINS[2]

　　3. repair DNA damage

　　4. support metabolism and promote energy production

　　5. Promotes vascular regeneration, maintains vascular elasticity, and enhances endurance and vitality

　　6. aids weight management

　　7. promotes heart health

　　8. promotes brain health

　　9. Improves insulin sensitivity

　　10. Prevents loss of bone density, improves vision and immune function, etc.